Thermo Fisher Scientific SERCA2 ATPase Polyclonal Antibody
Rabbit polyclonal antibody recognizing human SERCA2 ATPase. Validated for IHC and ICC applications. Supplied as liquid form with 0.1 mg/mL concentration. Ideal for calcium pump and muscle cell function studies. For research use only.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ATP2A2. Recombinant protein control fragment (Product #RP-101984). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2791709 |
Product Specific Information
Immunogen sequence:
TVEEVLGHFG VNESTGLSLE QVKKLKERWG SNELPA
Target Information
This gene encodes one of the SERCA Ca(2+)-ATPases, intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. The enzyme catalyzes ATP hydrolysis coupled with calcium translocation from cytosol into the sarcoplasmic reticulum lumen, regulating muscle contraction and relaxation cycles.
Mutations in this gene cause Darier-White disease (keratosis follicularis), an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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