Thermo Fisher Scientific MAGE1 Polyclonal Antibody
인간 MAGEA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 사용 가능. 고순도(>95%) 항체로 암 면역치료 연구에 활용. PBS/glycerol buffer에 1 mg/mL 농도로 제공.
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Thermo Fisher Scientific MAGE1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein of human MAGEA1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803884 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Human malignant neoplasms carry rejection antigens recognized by autologous, tumor-directed, and specific cytolytic CD8+ T lymphocyte clones (CTL). An important group of these antigens is coded by the MAGE family of genes, identified as melanoma-associated antigens (MAAs).
MAGE-1 is expressed in a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, and renal cell carcinomas) but not in normal tissues. Therefore, the encoded antigen may serve as a marker for early detection and as a target for cancer immunotherapy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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