Thermo Fisher Scientific GTF3A Polyclonal Antibody
GTF3A 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 인간 시료에 반응합니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from internal region of human GTF3A (UniProt ID: Q92664-1, range 17–43, length 365 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635599 |
Product Specific Information
This antibody detects endogenous levels of total TFIIIA / GTF3A protein.
Target Information
GTF3A encodes a zinc finger protein with nine Cys(2)-His(2) zinc finger domains. It functions as an RNA polymerase III transcription factor that induces transcription of 5S rRNA genes. The protein binds to a 50 bp internal promoter region (ICR) within the 5S genes and forms a stable preinitiation complex, recruiting TFIIIC, TFIIIB, and RNA polymerase III to complete transcription initiation. In mammals, translation may occur via a non-AUG initiation site based on sequence and homology analyses.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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