Thermo Fisher Scientific Toca-1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human TOCA-1 protein region 450–500. Validated for WB, IHC, IHC(P), and IP applications. Supplied as unconjugated liquid form at 1 mg/mL concentration. Recommended storage at 4°C with 1-year shelf life.
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Thermo Fisher Scientific Toca-1 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 450 and 500 of Human Transducer of Cdc42-Dependent Actin Assembly Protein 1 (TOCA-1, UniProt ID: Q5T0N5-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
The protein encoded by this gene contains a RING finger motif. The mouse counterpart interacts with Rela, the p65 subunit of NF-kappaB (NFKB), and modulates NFKB-mediated transcription activity. It also binds ubiquitin-conjugating enzymes (E2s) and serves as a substrate for E2-dependent ubiquitination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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