Thermo Fisher Scientific TP53I11 Polyclonal Antibody
Human TP53I11 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 1:200–1:500 희석으로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액에 보관. 종양 억제 관련 연구용으로 적합.
- 카탈로그번호
- PA563770
- 판매단위
- pk
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TP53I11. Recombinant protein control fragment (Product # RP-101957) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2648835 |
Product Specific Information
- Immunogen sequence: AFPDQLYDAV FDGAQVTSKT
- Highest antigen sequence identity: Mouse - 90%, Rat - 90%
Target Information
TP53I11 is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family.
The PIG gene family encodes redox-controlling proteins involved in p53 tumor suppressor activity.
It is suggested that PIG11 participates in arsenic trioxide [As(2)O(3)]-induced apoptosis and may play a significant role in tumor suppression through promotion of cell apoptosis.
The gene encoding PIG11 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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