Thermo Fisher Scientific ITM2B Monoclonal Antibody (OTI1C11), TrueMAB
인간 ITM2B 단백질을 인식하는 Mouse IgG2a 단일클론 항체. Western blot, IHC, Flow cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제, 안정한 PBS/BSA/glycerol 버퍼 저장. 알츠하이머 및 신경퇴행성 질환 연구용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1C11 |
| Immunogen | Full-length human recombinant protein of ITM2B produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer’s disease.
This gene encodes a transmembrane protein processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide that inhibits beta-amyloid deposition.
Mutations extending the C-terminal end of the encoded protein are associated with familial British dementia and familial Danish dementia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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