Thermo Fisher Scientific STAT6 Polyclonal Antibody
STAT6 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, IHC, ICC, Flow Cytometry, ELISA 등 다양한 응용에 사용 가능. 인간, 마우스, 랫트 반응성. Protein A 정제, 액상 형태, 고농도(1 mg/mL)로 안정적이며 연구용으로 적합.
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Thermo Fisher Scientific STAT6 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human STAT6 (amino acids 601–700) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
STAT6 protein is a transcription factor activated by cytokines such as interleukin-4 (IL-4) and IL-13. STAT6-deficient (Stat6-/-) models show impaired IL-4-mediated functions including Th2 helper T-cell differentiation, expression of cell surface markers, T-cell proliferation, immunoglobulin class switching to IgE, and reduced IL-4-mediated proliferation.
STAT6 mRNA is expressed in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta.
STAT6 plays a critical role in Th2 immune response and IL-4-mediated biological processes, existing in two isoforms: STAT6a and STAT6c.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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