Thermo Fisher Scientific NNT1 Polyclonal Antibody
Thermo Fisher Scientific의 NNT1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하며 IHC(P) 분석에 적합합니다. Rabbit IgG 폴리클로날 항체로, 합성 펩타이드(aa 171-220)를 면역원으로 사용했습니다. 액상 형태, 1 mg/mL 농도, -20°C 보관 조건입니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:300
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human NNT1 (aa 171–220) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS (pH 7.4) with 50% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2688436 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
NNT-1/BCSF-3 is a neurotrophic factor with B-cell-stimulating capabilities. It is expressed in the lymph nodes and spleen and activates glycoprotein 130 (gp130) and leukemia inhibitory factor receptor member b (LIFR-b) by binding and inducing tyrosine phosphorylation of these receptors.
In vitro, it supports the survival of chick embryo motor and sympathetic neurons. In mice, NNT-1/BCSF-3 induces serum amyloid A, causes body weight loss, and B cell hyperplasia associated with increases in serum IgG and IgM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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