Thermo Fisher Scientific FBXW5 Polyclonal Antibody
Thermo Fisher Scientific의 FBXW5 Polyclonal Antibody는 인간 FBXW5 단백질을 인식하는 rabbit polyclonal 항체로, Western blot 및 IHC(P) 분석에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA531635
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 177–432 of Human FBXW5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549108 |
Product Specific Information
- Recommended positive control: HeLa
- Predicted reactivity: Bovine (80%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif. F-box proteins are subunits of ubiquitin protein ligase complexes (SCFs: SKP1–Cullin–F-box) involved in phosphorylation-dependent ubiquitination.
They are divided into three classes:
- Fbws – containing WD-40 domains
- Fbls – containing leucine-rich repeats
- Fbxs – containing other interaction modules or no recognizable motifs
The FBXW5 protein contains WD-40 domains and an F-box motif, belonging to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified but are considered nonsense-mediated decay candidates.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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