Thermo Fisher Scientific FEN1 Monoclonal Antibody (1E2)
FEN1 단백질을 인식하는 Mouse IgM 단일클론 항체로 Western blot 및 ELISA에 적합. 인간 FEN1에 반응하며 DNA 복제 및 수선 연구용으로 사용. 액상 형태, 보존제 없음, -20°C에서 보관.
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Thermo Fisher Scientific FEN1 Monoclonal Antibody (1E2)
Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
- ELISA: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgM, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1E2 |
| Immunogen | FEN1 (NP_004102, 1–110 a.a) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MGIQGLAKLI ADVAPSAIRE NDIKSYFGRK VAIDASMSIY QFLIAVRQGG DVLQNEEGET TSHLMGMFYR TIRMMENGIK PVYVFDGKPP QLKSGELAKR SERRAEAEKQ
Target Information
FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 kDa protein that functions as an endonuclease cleaving branched DNA structures containing single-stranded 5′ flaps or as an exonuclease on DNA nicks and gaps.
Its activities are stimulated by association with proliferating cell nuclear antigen (PCNA) in the nucleus.
FEN-1 plays important roles in DNA replication and repair and is required in cell-free DNA replication systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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