Thermo Fisher Scientific Neurogenin 2 Recombinant Rabbit Monoclonal Antibody (8F2Q8)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

8F2Q8

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human Neurogenin 2. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Neurogenin 2,uniProtId:Q9H2A3-1,ncbiNodeId:9606,antigenRange:50-150,antigenLength:272,antigenImageFileName:MA5-55298_Neurogenin_2_Q9H2A3-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55298_Neurogenin_2_Q9H2A3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: GARRQRGAEA GQGARGGVAA GAEGCRPARL LGLVHDCKRR PSRARAVSRG AKTAETVQRI KKTRRLKANN RERNRMHNLN AALDALREVL PTFPEDAKLT K

Target Information

Neurogenin-2 is a member of the neurogenin subfamily of basic helix-loop-helix (bHLH) transcription factor genes that play an important role in neurogenesis from migratory neural crest cells. In the course of mouse neurogenesis, Ngn2 and Ngn1 are expressed in distinct progenitor populations residing in the central and peripheral nervous systems. Mutation analyses demonstrate that Ngn1 is required for the determination of neuronal precursors for proximal cranial sensory ganglia and that Ngn2 is necessary for the determination of precursors for epibranchial placode-derived sensory neurons.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.