Thermo Fisher Scientific CD8 beta Monoclonal Antibody (3.4.1), FITC
Flow Cytometry용 FITC 결합 CD8 beta 단클론 항체로, Rat CD8b를 특이적으로 인식합니다. Mouse IgG1 아이소타입이며 Protein G로 정제되었습니다. 498/517 nm의 형광 특성을 가지며, BSA와 sodium azide를 포함한 PBS buffer에 저장됩니다.
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Applications
- Flow Cytometry (Flow): 0.5 µg/1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 3.4.1 |
| Immunogen | Rat/mouse T cell hybrids expressing CD8 |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538980 |
Additional Formats
- Unconjugated: MA1-70040
- Biotin: MA5-17588
- PE: MA5-17592
- Custom conjugation available upon request
Target Information
The CD8B antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a coreceptor with the T-cell receptor to recognize antigens presented by APCs in the context of class I MHC molecules. The functional coreceptor can be either a homodimer (alpha chains) or a heterodimer (alpha and beta chains). Both chains show significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms, with multiple alternatively spliced transcript variants encoding distinct membrane-associated or secreted isoforms. A pseudogene on chromosome 2 has also been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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