Thermo Fisher Scientific HSJ1 Polyclonal Antibody
HSJ1(DNAJB2) 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. IHC, ICC/IF, ELISA 등 다양한 응용 가능. 고순도 Protein A 정제, 안정적 액상 형태로 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human HSJ1/DNAJB2, amino acids 21–120 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The DnaJ family is one of the largest chaperone families, characterized by the presence of a J domain. These proteins interact with HSP70 to stimulate ATP hydrolysis and contain cysteine-rich zinc finger regions forming peptide-binding domains essential for chaperone function. DnaJ proteins mediate proteolysis and regulate protein degradation, exocytosis, and endocytosis.
DnaJB2 (also known as HSJ1 or HSPF3) is expressed predominantly in the brain, especially in the frontal cortex and hippocampus. Two isoforms are produced via alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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