Thermo Fisher Scientific Interferon gamma (IFNG) Monoclonal Antibody (G-30)
인간 IFN-gamma를 인식하는 G-30 클론 단일클론 항체로, ICC/IF 및 유세포분석에 적합합니다. 비결합형 액상 형태이며, Protein A/G로 정제되었습니다. 연구용으로만 사용 가능하며, -20°C에서 보관합니다.
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Thermo Fisher Scientific Interferon gamma (IFNG) Monoclonal Antibody (G-30)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G-30 |
| Immunogen | Purified recombinant human IFN-gamma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Interferon gamma (IFNγ, Type II interferon) is a macrophage activation factor produced mainly by T-lymphocytes and natural killer cells in response to antigens and cytokines. It is a dimeric glycoprotein composed of two 146 amino acid subunits (~45 kDa as a homodimer). IFNγ exhibits species-specific biological activity and does not cross-react between human and mouse. Its functions include antiviral and antiproliferative activity, induction of MHC class I and II, macrophage activation, and enhanced immunoglobulin secretion by B cells. IFNγ acts through IFNγ receptor I and II, activating the JAK-STAT pathway. It shares ~40% sequence homology with mouse IFNγ and is regulated by IL2, FGF basic, EGF, and downregulated by vitamin D3 or DMN. Mutations in the IFNγ gene are associated with aplastic anemia.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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