Thermo Fisher Scientific SLC30A8 Polyclonal Antibody
SLC30A8 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. 인간 시료에 반응하며, ICC/IF에 적합. 아연 수송 관련 연구 및 당뇨병 관련 유전자 연구에 활용 가능. 0.4 mg/mL 농도의 액상 형태로 제공.
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- PA5144933
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 315–369). Recombinant protein control fragment (Product # RP-108278) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_3092048 |
Product Specific Information
Immunogen sequence:
LSAHVATAAS RDSQVVRREI AKALSKSFTM HSLTIQMESP VDQDPDCLFC EDPCD
Antigen sequence identity:
Mouse 73%; Rat 73%
Target Information
Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans. It co-localizes with insulin in the secretory granules of insulin-secreting INS-1 cells. Allelic variants of Slc30A8 are major genetic risk factors for Type 2 diabetes, though no association has been found with Type 1 diabetes. Expression in β-cells is influenced by cytokines, especially IFN-γ and IL-1β.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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