
Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI5D9), TrueMAB
인간 CD4 단백질을 인식하는 mouse monoclonal 항체로, Western blot과 IHC(P) 실험에 적합합니다. Affinity chromatography로 정제되었으며, PBS/BSA/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5D9 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. CD4 is primarily expressed in T helper cells but can also be found in monocytes, macrophages, and dendritic cells. It is expressed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 aids in T-cell activation through interaction with the T-cell receptor complex and protein tyrosine kinase Lck, and may mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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