Thermo Fisher Scientific PRPF18 Polyclonal Antibody
Human PRPF18 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태. 0.2 mg/mL 농도로 PBS 및 글리세롤 완충액에 보관. 연구용으로만 사용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific PRPF18 Polyclonal Antibody
Thermo Fisher Scientific PRPF18 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PRPF18. Recombinant protein control fragment (Product #RP-104435). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645969 |
Product Specific Information
- Immunogen sequence:
EPGEEDTQND LKVHEENTTI EELEALGESL GKGDDHKDMD IITKFLKFLL GVWAKELNAR EDYVKRSVQG KLNSATQKQT ES - Highest antigen sequence identity to orthologs:
Mouse - 100%, Rat - 99%.
Target Information
PRPF18 (pre-mRNA-splicing factor 18), also known as HPRP18, is a 342 amino acid protein that localizes to nuclear speckles and plays a role in the second step of pre-mRNA splicing.
A member of the PRP18 family, PRPF18 contains seven WD repeats and exists as two alternatively spliced isoforms encoded by a gene located on human chromosome 10p13.
Chromosome 10 contains over 800 genes and 135 million nucleotides. PTEN, an important tumor suppressor gene located on chromosome 10, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome.
Other chromosome 10 associated disorders include Cockayne syndrome, tetrahydrobiopterin deficiency, and trisomy 10.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.