Thermo Fisher Scientific ADC Polyclonal Antibody
Thermo Fisher Scientific의 ADC Polyclonal Antibody는 인간 ADC 단백질을 인식하는 토끼 다클론 항체로, Western blot에 적합합니다. 고순도 항원 친화 크로마토그래피로 정제되었으며, 다양한 종과 교차 반응성을 보입니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 121–359 of Human ADC |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.02 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2549224 |
Product Specific Information
- Recommended positive controls: SK-N-SH, human normal cerebellar
- Predicted reactivity: Mouse (85%), Rat (86%), Dog (88%), Cat (88%), Pig (89%), Rabbit (90%), Sheep (86%), Rhesus Monkey (96%), Bovine (86%), Guinea pig (85%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Antizyme inhibitor 2 (AzI2), also known as arginine decarboxylase (ADC), is an enzyme encoded by the AZIN2 gene in humans. It belongs to the antizyme inhibitor family, which regulates cell growth and proliferation by maintaining polyamine homeostasis.
Antizyme inhibitors are homologs of ornithine decarboxylase (ODC) that can bind antizymes but lack decarboxylase activity. They act as positive regulators of polyamine levels by sequestering antizymes.
Antizyme inhibitor 2 is predominantly expressed in the brain and testis, localized in the endoplasmic reticulum–Golgi intermediate compartment, and may play roles in cell growth, spermiogenesis, vesicular trafficking, and secretion.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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