Thermo Fisher Scientific Human CaMKI (aa 1-18) Synthetic Peptide

Applications

Tested Dilution

Publications

Control (Ctrl)

Assay-dependent

-

Product Specifications

Class

Synthetic

Type

Peptide

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

Product Specific Information

PEP-134 is an 18 amino acid synthetic peptide whose sequence corresponds to amino acid residues 1-18 from human CaMKI protein. The sequence of this peptide is (amino to carboxy terminus): A (1)-V-E-G-P-R-W-K-Q-A-E-D-I-R-D-I-Y-D (18).

This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and human CaMKI protein, catalog # PA1-543. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~70-fold) for competitive inhibition of antibody-protein binding reactions.

Reconstitute with 0.1 mL of distilled water.

Target Information

CAMK1 (CaMK1) is a serine/threonine kinase that is a member of the calcium/calmodulin-dependent protein kinase family. It is involved in cell differentiation, nervous system development, and signal transduction. CAMK1 is expressed in many tissues and is a component of a calmodulin-dependent protein kinase cascade. Calcium/calmodulin directly activates calcium/calmodulin-dependent protein kinase I by binding to the enzyme and indirectly promotes the phosphorylation and synergistic activation of the enzyme by calcium/calmodulin-dependent protein kinase I kinase.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.