Thermo Fisher Scientific ROPN1L Polyclonal Antibody
ROPN1L 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot과 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 버퍼에 보관. 인간 시료에 반응하며, 정자 운동성과 세포 골격 재구성 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ROPN1L. Recombinant protein control fragment (Product #RP-102916). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2646700 |
Product Specific Information
Immunogen sequence:
PDTMFCAQQI HIPPELPDIL KQFTKAAIRT QPADVLRWSA GYFSALSRGD PLPVKDRMEM PTATQKTDTG LTQGLL
Sequence identity:
Highest antigen sequence identity to the following orthologs: Mouse – 96%, Rat – 96%.
Target Information
Principal Names: ROPN1L; Ropporin-1 like; ASP; AKAP-associated sperm protein
Official Gene Symbol: ROPN1L
Gene ID: 83853 (human)
Gene Map Locus: 5p15.2 (human)
AKAPs act as scaffolding proteins coordinating phosphatase/kinase signaling at the cytoskeleton. They interact with PKAs and anchor them to specific sub-cellular compartments and participate in multiple cellular processes including growth, metabolism, and differentiation.
ASP, a 26 kDa protein, is a novel AKAP-interacting protein. It interacts with the amphipathic helix of AKAP3 and facilitates AKAP3-PKA interactions. It consists of a conserved N-terminal AKAP-binding domain and a central cysteine-rich Fz domain. It is specifically expressed in sperm and might play a significant role in sperm motility and cytoskeletal reorganization during spermiogenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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