Thermo Fisher Scientific ERK2 Monoclonal Antibody (4C11)
ERK2 단백질을 검출하기 위한 Thermo Fisher Scientific의 Mouse Monoclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 인간, 마우스, 비인간 영장류 시료에 반응. 고순도 Protein G 정제 및 안정적인 액상 형태.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 |
| Immunocytochemistry (ICC/IF) | 1:200–1:1,000 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C11 |
| Immunogen | Purified recombinant fragment of human ERK2 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10980249 |
Product Specific Information
MA5-15304 targets ERK2 in indirect ELISA, IF, IHC, and WB applications and shows reactivity with human, mouse, and non-human primate samples.
The immunogen is a purified recombinant fragment of human ERK2 expressed in E. coli.
MA5-15304 detects ERK2, which has a predicted molecular weight of approximately 41 kDa.
Target Information
MAPK1 (ERK2) is a serine/threonine kinase acting as an important activator of p90 RSK, MSK, ELK1, and Stat3, and is involved in the MAPK pathway.
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), serve as integration points for multiple biochemical signals and are involved in various cellular processes such as proliferation, differentiation, transcription regulation, and development.
Activation of this kinase requires phosphorylation by upstream kinases. Upon activation, ERK2 translocates to the nucleus of stimulated cells, where it phosphorylates nuclear targets.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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