Thermo Fisher Scientific MAST2 Polyclonal Antibody
Rabbit polyclonal antibody against MAST2 for Western blot and immunoprecipitation. Targets region 1748–1798 of human MAST2. Supplied as unconjugated liquid at 1 mg/mL. Stored at 4°C and shipped on wet ice. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1748 and 1798 of human microtubule associated serine/threonine kinase 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
Target Information
Syntrophin is an adapter protein that binds signaling molecules to the dystrophin-associated protein complex, linking the extracellular matrix to the intracellular cytoskeleton for postsynaptic structure maintenance in the neuromuscular junction and CNS.
Microtubule-associated serine/threonine-protein kinase 2 (MAST205) is a testis-specific cytoplasmic protein functioning in spermatid maturation. It links the dystrophin/utrophin network with microtubule filaments via Syntrophin and regulates IL-12 synthesis in macrophages through TRAF6 complex formation, inhibiting TRAF6 NF-kappa-B activation.
Two isoforms exist due to alternative splicing: isoform 1 (full length) and isoform 2 (lacking residues 327–396 and 1091–1113). Phosphorylation at the N-terminus enables ubiquitination and subsequent proteasome-mediated degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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