Thermo Fisher Scientific NOX2 Polyclonal Antibody
NOX2 단백질을 인식하는 Thermo Fisher Scientific의 염소 유래 다클론 항체로, Western blot에 최적화되어 있습니다. 인간과 생쥐 시료에 반응하며, 고순도 정제 및 안정적인 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence CDKQEFQDAWKLPK (aa 371–384) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933292 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:8,000.
Target Information
Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase.
The superoxide-generating NADPH oxidase complex expresses in phagocytes, neuroepithelial bodies, vascular smooth muscle cells, and endothelial cells.
It includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox.
The p22- and gp91-phox subunits also function as surface O₂ sensors that initiate cellular signaling in response to hypoxic conditions.
Mox1 and gp91 contain identical C-terminal sequence identity, yet possess distinct expression patterns.
gp91-phox expresses in eosinophils, neutrophils, monocytes, and B-lymphocytes, whereas Mox1 is predominantly detected in the colon, with low expression in the uterus and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: PA5-142646_NOX2_P04839-1_Goat.svg, PA5-142646_NOX2_P04839-1_Goat_PDP.jpeg)
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