Thermo Fisher Scientific RUNX1 Monoclonal Antibody (4E7)
RUNX1 단백질을 인식하는 Mouse monoclonal antibody (Clone 4E7). Western blot, IHC, ICC/IF, ELISA에 적합. Human 시료 반응성. PBS buffer에 보존, 무보존제. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4E7 |
| Immunogen | RUNX1 (NP_001001890.1, 210 a.a. – approximately 310 a.a) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RVSPHHPAPT PNPRASLNHS TAFNPQPQSQ MQDTRQIQPS PPWSYDQSYQ YLGSIASPSV HPATPISPGR ASGMTTLSAE LSSRLSTAPD LTAFSDPRQF P
Target Information
RUNX1 belongs to the mammalian RUNX family of DNA binding proteins that regulate the expression of genes involved in cellular differentiation and cell cycle progression.
RUNX1 is essential for hematopoietic stem cell generation in the vascular regions of the aorta, vitelline and umbilical arteries, yolk sac, and placenta.
RUNX1 is expressed in all tissues except brain and heart, with highest levels in thymus, bone marrow, and peripheral blood.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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