Thermo Fisher Scientific SGEF Polyclonal Antibody
Human SGEF 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot 및 IHC(Paraffin)에서 검증됨. Antigen affinity chromatography로 정제된 액상 형태이며, 연구용으로만 사용 가능. RhoG GTPase 활성화 관련 연구에 적합.
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Thermo Fisher Scientific SGEF Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SGEF. Recombinant protein control fragment (Product #RP-90732) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2647211 |
Product Specific Information
Immunogen sequence:
PEEDLTGLTA SPVPSPTANG LAANNDSPGS GSQSGRKAKD PERGLFPGPQ KSSSEQKLPL QRLPSQENEL LENPSVVLST NSPAALKVGK QQIIPKSLAS EIKISKSNNQ NV
Highest antigen sequence identity to orthologs:
- Mouse: 70%
- Rat: 71%
Target Information
Activates RhoG GTPase by promoting the exchange of GDP for GTP. Required for the formation of membrane ruffles during macropinocytosis and cup-like structures during trans-endothelial migration of leukocytes. In case of Salmonella enterica infection, activated by SopB, which induces cytoskeleton rearrangements and promotes bacterial entry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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