Thermo Fisher Scientific EMX2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human EMX2 for WB, IHC, and ELISA applications. High specificity with antigen affinity purification. Suitable for research use only. Stored at 4°C or -20°C for long-term stability.
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1.0–2.0 µg/mL | |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2.5 µg/mL | |
| ELISA | Assay-Dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | EMX2 antibody raised against an 18 amino acid synthetic peptide near the center of human EMX2 (amino acids 60–110). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2718597 |
Target Information
This gene encodes a homeobox-containing transcription factor homologous to the empty spiracles gene in Drosophila. In humans, EMX2 is expressed in the dorsal telencephalon, olfactory neuroepithelium, and urogenital system. During development, its expression in the dorsal telencephalon follows a low rostral-lateral to high caudal-medial gradient, contributing to neocortex patterning. In olfactory neuroepithelia, EMX2 interacts with eukaryotic translation initiation factor 4E (eIF4E), potentially regulating mRNA transport or translation. In the developing urogenital system, EMX2 expression occurs in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing generates multiple transcript variants encoding distinct proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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