Thermo Fisher Scientific mPR gamma Polyclonal Antibody
Rabbit polyclonal antibody against human mPR gamma (PAQR5), reactive with human, mouse, and rat. Suitable for WB, IHC, and ICC applications. Affinity-purified, supplied as a liquid at 1 mg/mL in PBS with glycerol. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human PAQR5 (Accession Q9NXK6), corresponding to amino acid residues A296–T330 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854510 |
Product Specific Information
Antibody detects endogenous levels of total MPRG.
Target Information
The steroid progesterone induces the resumption of maturation in oocytes via a nongenomic pathway through binding to a novel membrane progestin receptor (mPR). This pathway inhibits adenylyl cyclase, reduces intracellular cAMP, and activates mitogen-activated protein kinase to effect signal transduction pathways. Three distinct groups—alpha, beta, and gamma—comprise this gene family. While all contain seven transmembrane domains, they show distinct distributions in reproductive, neural, kidney, and intestinal tissues. These characteristics separate them from nuclear progestin receptors and imply similarity to G-protein coupled receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-106846_mPR_gamma_Q9NXK6-1_Rabbit.svg, PA5-106846_mPR_gamma_Q9NXK6-1_Rabbit_PDP.jpeg)
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