Thermo Fisher Scientific SULT1A1 Monoclonal Antibody (3F10)

Thermo Fisher Scientific SULT1A1 Monoclonal Antibody (3F10)

Applications

• Western Blot (WB)
  Tested Dilution: -
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• Immunoprecipitation (IP)
  Tested Dilution: 1–2 µL
  View 1 publication

Product Specifications

Product Specific Information

A suggested positive control for this product is mouse brain.

Target Information

The soluble sulfotransferases contribute to the elimination of xenobiotics, the activation of procarcinogens, and the regulation of hormones by catalyzing the sulfate conjugation of these substances.
Members of the three groups comprising this superfamily (SULT1, SULT2, and SULT3) show selectivity to certain substrate compounds.

SULT1A1 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1), also known as STP or STP1, is a 295 amino acid protein that localizes to the cytoplasm and belongs to the sulfotransferase family.
Functioning as a homodimer expressed in brain, liver, skin, and lung tissue, SULT1A1 catalyzes the sulfate conjugation of catecholamines, phenolic drugs, and neurotransmitters, playing a role in the elimination of various compounds from the body.
Additionally, SULT1A1 may be involved in the activation of carcinogenic N-hydroxyarylamines, indicating a possible role in carcinogenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.