Thermo Fisher Scientific IGHA1 Polyclonal Antibody
Rabbit polyclonal antibody against human IGHA1 for WB and IHC applications. Recognizes constant region of immunoglobulin heavy chains. High purity (>95%), antigen affinity purified, unconjugated form. Supplied in PBS with glycerol and sodium azide, sui...
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Thermo Fisher Scientific IGHA1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 241–290 of Human IgA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803349 |
Product Specific Information
Purity is >95% by SDS-PAGE.
Target Information
Constant region of immunoglobulin heavy chains. Immunoglobulins (antibodies) are membrane-bound or secreted glycoproteins produced by B lymphocytes.
In the recognition phase of humoral immunity, membrane-bound immunoglobulins act as receptors that, upon binding a specific antigen, trigger clonal expansion and differentiation of B lymphocytes into plasma cells.
Secreted immunoglobulins mediate the effector phase of humoral immunity, eliminating bound antigens. The antigen binding site is formed by the variable domains of one heavy chain and its associated light chain, providing two antigen binding sites per molecule.
Variable domains are assembled through V-(D)-J rearrangement and undergo somatic hypermutation for affinity maturation. Ig alpha is the major immunoglobulin class in body secretions. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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