Thermo Fisher Scientific Phospho-4EBP1 (Thr70) Polyclonal Antibody
Phospho-4EBP1 (Thr70) 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응합니다. Western blot, IHC(P), ELISA에 사용 가능하며, 고순도 친화 크로마토그래피 정제 제품입니다. PBS/glycerol 완충액에 보관되며, -20°C에서 안정적으로 유지됩니다.
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- PA5110116
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphorylated peptide around T70 of human Phospho-eIF4EBP1-T70 (NP_0040861) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2855527 |
Product Specific Information
Immunogen sequence: TKTPP
Target Information
This gene encodes a member of the family of translation repressor proteins.
The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5′ end of mRNAs.
Interaction with eIF4E inhibits complex assembly and represses translation.
Phosphorylation in response to signals such as UV irradiation and insulin signaling causes dissociation from eIF4E and activation of mRNA translation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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