Thermo Fisher Scientific CERKL Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1:500–1:1,000

Product Specifications

Target Information

This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains; however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may act as a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
[Provided by RefSeq, May 2010]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.