Thermo Fisher Scientific V-ATPase D Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:3,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:100–1:1,000

Product Specifications

Product Specific Information

• Recommended positive controls: U87-MG, mouse brain
• Predicted reactivity: Mouse (97%), Rat (98%), Zebrafish (86%), Rabbit (98%), Chicken (93%), Rhesus Monkey (100%), Bovine (98%)
• Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles.
V-ATPase-dependent organelle acidification is essential for intracellular processes such as:

• Protein sorting
• Zymogen activation
• Receptor-mediated endocytosis
• Synaptic vesicle proton gradient generation

V-ATPase consists of:

• V1 domain: three A, three B, two G subunits plus C, D, E, F, and H subunits (ATP catalytic site)
• V0 domain: five subunits (a, c, c′, c″, and d)

Multiple isoforms are encoded by distinct genes or alternatively spliced transcript variants.
This gene encodes the V1 domain D subunit protein.

⚠ WARNING: This product can expose you to chemicals including mercury, known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(PA5-31371_V-ATPase_D_Q9Y5K8-1_Rabbit.svg 및 PA5-31371_V-ATPase_D_Q9Y5K8-1_Rabbit_PDP.jpeg 이미지 참조)