Thermo Fisher Scientific CD200R Monoclonal Antibody (380525)
인간 CD200R 단백질을 인식하는 Mouse 모노클로날 항체. Western blot과 유세포분석에 적합하며, 비특이적 반응 없이 높은 특이성 제공. 동결건조 형태로 제공되며, PBS와 trehalose 완충액에 재구성 가능. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 380525 |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human CD200 R1 (Ala27–Leu266, predicted) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2606431 |
Product Specific Information
- In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse CD200 R1 is observed.
- Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
CD200R (OX2R) is a receptor for the OX-2 membrane glycoprotein. Both receptor and substrate are cell surface glycoproteins containing two immunoglobulin-like domains.
CD200R is expressed on myeloid lineage cells and acts as a myeloid downregulatory signal.
In mice, CD200R is expressed primarily by peripheral blood monocytes and neutrophils, as well as T-lymphocytes and mast cells.
Alternative splicing of CD200R results in multiple transcript variants.
Diseases associated with CD200R dysfunction include primary hypertrophic osteoarthropathy.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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