Thermo Fisher Scientific TAX1BP1 Recombinant Rabbit Monoclonal Antibody (7Y9W3)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

7Y9W3

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 690-789 of human TRAF6BP/TAX1BP1. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAX1BP1,uniProtId:Q86VP1-1,ncbiNodeId:9606,antigenRange:690-789,antigenLength:789,antigenImageFileName:MA5-55580_TAX1BP1_Q86VP1-1_Rabbit.svg,antigenImageFileNamePDP:MA5-55580_TAX1BP1_Q86VP1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.28 mg/mL

Purification

Protein A

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Product Specific Information

Immunogen Sequence: DSEDSKEDEN VPTAPDPPSQ HLRGHGTGFC FDSSFDVHKK CPLCELMFPP NYDQSKFEEH VESHWKVCPM CSEQFPPDYD QQVFERHVQT HFDQNVLNFD

Target Information

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.