Thermo Fisher Scientific Adrenomedullin Monoclonal Antibody (OTI8A1)
Adrenomedullin 단백질(AA 22-146)을 인식하는 Mouse IgG2b 단클론 항체. IHC(P)에서 1:250 희석으로 사용 가능. 액상 형태, 1 mg/mL 농도. PBS/BSA/glycerol buffer에 보관하며 -20°C에서 냉동 보존. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:250
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8A1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 22–146 of ADM produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722821 |
Target Information
Adrenomedullin (ADM) is a vasodilator produced by contractile cells and exhibits persistent hypotensive activity. It plays a role in regulating fluid and electrolyte homeostasis and maintaining cardiovascular function. In hypertensive patients, plasma ADM levels are elevated. ADM induces natriuresis through increased glomerular filtration and decreased distal tubular sodium reabsorption. Present in both peripheral tissues and the brain, ADM also exerts central effects such as reducing food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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