Thermo Fisher Scientific NPDC1 Polyclonal Antibody
인간 NPDC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. N-말단 합성 펩타이드로 면역화되었으며, Protein A로 정제된 액상 항체입니다. PBS(2% sucrose) 완충액에 보관하며 -20°C에서 안정적으로 저장 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2.5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human NPDC1 (aa 1–50) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2577064 |
Product Specific Information
Peptide sequence:
MATPLPPPSP RHLRLLRLLL SGLVLGAALR GAAAGHPDVA ACPGSLDCAL
Sequence homology:
Cow: 93%
Dog: 93%
Human: 100%
Mouse: 93%
Rat: 93%
Yeast: 83%
Target Information
The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. Transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and interacts directly with the transcription factor E2F-1, D-type cyclins, and cdk2. It modulates transcriptional events mediated by retinoic acid, and its protein level and activity are regulated by phosphorylation-mediated proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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