Thermo Fisher Scientific CEP78 Polyclonal Antibody
CEP78 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC(P), ICC/IF에 사용 가능. 인간 및 마우스 반응성. Affinity chromatography로 정제된 1 mg/mL 액상 제품으로, -20°C에서 보관. 연구용 전용.
- 카탈로그번호
- PA5101512
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CEP78 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CEP78 (Accession Q5JTW2), corresponding to amino acid residues V309–A359 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850947 |
Product Specific Information
Antibody detects endogenous levels of total CEP78.
Target Information
The CEP78 gene encodes a centrosomal protein essential for regulating centrosome-related events during the cell cycle and for ciliogenesis. The protein includes an N-terminal leucine-rich repeat (LRR) domain with six LRR repeats and a C-terminal coiled-coil domain. It interacts with the N-terminal catalytic domain of polo-like kinase 4 (PLK4) and colocalizes with PLK4 at the distal end of the centriole. Mutations in this gene can cause primary cilia defects leading to retinal degeneration and sensorineural hearing loss, associated with cone-rod degeneration disease and Usher syndrome. Low expression of CEP78 is linked to poor prognosis in colorectal cancer patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.