Thermo Fisher Scientific REST Polyclonal Antibody
REST 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal antibody입니다. Western blot 및 Peptide ELISA에 검증되었으며, 인간 시료에 반응합니다. 고순도 액상 형태로 제공되며 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Thermo Fisher Scientific REST Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.3–1 µg/mL
Publications: - [References not provided]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-PETPGAEDKGKSSK |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C (Avoid Freeze/Thaw Cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_2933877 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
Target Information
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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