Thermo Fisher Scientific D4 Dopamine Receptor Polyclonal Antibody
D4 도파민 수용체를 인식하는 Rabbit Polyclonal 항체로 인간, 생쥐, 랫트 반응성. Western blot, IHC, ICC/IF에 사용 가능. Affinity chromatography로 정제된 액상 형태, 1 mg/mL 농도. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DRD4 (Accession P21917), corresponding to amino acid residues A363–V413 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853693 |
Product Specific Information
This antibody detects endogenous levels of total DRD4.
Target Information
The D4 dopamine receptor is a G-protein coupled receptor that inhibits adenylyl cyclase. It is a pharmacological target for drugs treating schizophrenia and Parkinson’s disease. Mutations in the DRD4 gene are associated with behavioral phenotypes such as autonomic nervous system dysfunction, ADHD, and novelty seeking. The gene contains a polymorphic number (2–10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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