Thermo Fisher Scientific TNFRSF25 Polyclonal Antibody
Human TNFRSF25 단백질을 인식하는 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Protein A 정제, 1 mg/mL 농도, -20°C 보관. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TNFRSF25 (amino acids 25–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01 M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
DR3/TNFRSF25 is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in lymphocyte-enriched tissues and may regulate lymphocyte homeostasis. It stimulates NF-kappa B activity and regulates apoptosis through death domain-containing adaptor proteins. Knockout studies in mice indicate its role in removing self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants encode distinct isoforms, many of which are secreted. Upon T-cell activation, alternative splicing predominantly produces full-length, membrane-bound isoforms involved in controlling lymphocyte proliferation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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