Thermo Fisher Scientific CD23 (Fc Epsilon RII) Recombinant Rabbit Monoclonal Antibody (FCER2/4395R)
인간 CD23(Fc Epsilon RII)을 인식하는 재조합 토끼 단클론 항체. IHC 및 펩타이드 어레이 등 다양한 분석에 사용 가능. HEK293 세포 발현, Protein A/G 정제. 4°C 보관, 동결 금지. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | FCER2/4395R |
| Immunogen | Recombinant fragment (around aa 221–321) of human FCER2/CD23 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD23 is a 45 kDa glycoprotein present on a subset of peripheral blood and tonsil B cells, and is strongly expressed on EBV-transformed B lymphoblasts.
It is identical to the low affinity IgE receptor (FcεRII) found on B cells.
Expression of CD23 has been detected in neoplastic cells from B cell chronic lymphocytic leukemia and some lymphomas.
Functionally, CD23 is involved in B cell growth, differentiation, and IgE production.
Its soluble form acts as a potent mitogenic factor.
Diseases associated with CD23 dysfunction include chronic conjunctivitis and chronic lymphocytic leukemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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