Thermo Scientific™

GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 Cells

GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells contain the human Adenosine Receptor A2A (ADORA2A) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.자세히 알아보기

GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells contain the human Adenosine Receptor A2A (ADORA2A) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line. CellSensor™ CRE-bla CHO-K1 cells (Cat. No. K1535) contain a beta-lactamase reporter gene under control of the Cyclic AMP Response Element (CRE) response element.

The GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells are functionally validated for Z` and EC50 concentrations of NECA. In addition, GeneBLAzer™ ADORA2A-CRE-bla CHO-K1 cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

ADORA2A has been shown to have many roles throughout the body. ADORA2A is involved in pain and inflammation regulation, inhibition of platelet aggregation, blood pressure regulation and contributes to ischemic brain damage. Selective antagonists of the ADORA2A pathway are being tested as adjuvants to dopaminergic drugs to treat Parkinson`s disease and schizophrenia.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

사양

등록 번호NM_000675

어세이 입력Cell-based beta lactamase reporter gene

셀 상태Dividing Cells

검출 방법Fluorescence

용도(애플리케이션)FRET

유전자 기호ADORA2A

개체군 상태Single Cell Clone Origin

제품라인GeneBLAzer™

수량2 x 106 Cells

리포터 유전자BLA (Beta-Lactamase)

타겟 입력ADORA2A

세포주CHO-K1

System TypeGeneBLAzer™

Druggable TargetGPCR

Unit SizeEach