Thermo Fisher Scientific eIF4G3 Polyclonal Antibody
Human eIF4G3 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 버퍼에 보관. 단백질 번역 조절 연구 및 암 관련 연구에 활용 가능.
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Thermo Fisher Scientific eIF4G3 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human eIF4G3. Recombinant protein control fragment (Product #RP-94018). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640974 |
Product Specific Information
Immunogen sequence:
EFDSRRTLTS RGSMGREKND KPLPSATARP NTFMRGGSSK DLLDNQSQEE QRREMLETVK QLTGGVDVER NSTEAERNKT RESAKPEISA MSA
Ortholog sequence identity:
- Mouse: 81%
- Rat: 78%
Target Information
The protein encoded by this gene is part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome.
A microRNA (miR-520c-3p) negatively regulates synthesis of this protein, leading to a global decrease in protein translation and cell proliferation.
This protein is a key component of the anti-tumor activity of miR-520c-3p.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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