Thermo Fisher Scientific FANCL Polyclonal Antibody
Thermo Fisher Scientific의 FANCL 폴리클로날 항체는 인간 FANCL 단백질을 인식하며 Western blot 및 IHC(P) 실험에 적합합니다. 합성 펩타이드 면역원 기반으로 제작되었으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human FANCL |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576961 |
Product Specific Information
- Peptide sequence: ASGREHLITL KLKAKYPAES PDYFVDFPVP FCASWTPQVN SPQSSLISIY
- Sequence homology: Dog 93%; Human 100%; Rabbit 86%
Target Information
The Fanconi anemia complementation group (FANC) includes FANCA, FANCB, FANCC, FANCD1 (BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (BRIP1), FANCL, FANCM, and FANCN (PALB2).
Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.
These proteins form a common nuclear complex. The FANCL gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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