Thermo Fisher Scientific PSRC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PSRC1. Recombinant protein control fragment (Product #RP-100942). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PSRC1,uniProtId:Q6PGN9-1,ncbiNodeId:9606,antigenRange:3-79,antigenLength:363,antigenImageFileName:PA5-61931_PSRC1_Q6PGN9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61931_PSRC1_Q6PGN9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2646085

Product Specific Information

Immunogen sequence: DLEEDVRFIV DETLDFGGLS PSDSREEEDI TVLVTPEKPL RRGLSHRSDP NAVAPAPQGV RLSLGPLSPE KLEEILD

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 90%.

Target Information

PSRC1 is required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A and ANKRD53 to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.