Thermo Fisher Scientific TLN1/Talin-1 Polyclonal Antibody
Rabbit polyclonal antibody against human TLN1/Talin-1. Validated for WB and IP applications. Targets residues 2491–2541 of Talin-1. Supplied as liquid, 1 mg/mL, stored at 4°C. For research use only.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–10 µg/mg lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 2491 to 2541 of Human Talin-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Talin is a multifunctional constituent of cell-substratum attachment sites and a high molecular weight protein (225–235 kDa) found in various tissues and cell types. It is localized at a subset of adherens junctions and specialized cell-cell and cell-matrix associations characterized by filamentous actin at the cytoplasmic face of the junctional complex. In cultured cells, talin is absent from cell-cell junctions and found predominantly at adhesion plaques and in fibrillar streaks underlying cell surface fibronectin. Talin interacts with proteins localized at adhesion plaques, including vinculin and integrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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