Thermo Fisher Scientific TAX1BP1 Polyclonal Antibody
Human TAX1BP1 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. 연구용으로만 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TAX1BP1. Recombinant protein control fragment (Product #RP-101865) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2648242 |
Product Specific Information
Immunogen sequence:
ADAVAELKLN AMKKDQDKTD TLEHELRREV EDLKLRLQMA ADHYKEKFKE CQRLQKQINK LSDQSANNNN VFTKKTGNQQ KVNDASVNTD PATSASTVDV KPSPSAAEAD FDIVTKGQVC EMTKEIADKT EKYNK
Highest antigen sequence identity to the following orthologs:
- Mouse: 80%
- Rat: 79%
Target Information
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3 and inhibits TNF-induced apoptosis by mediating TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. It may also play a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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