Thermo Fisher Scientific TAX1BP1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human TAX1BP1. Recombinant protein control fragment (Product #RP-101865). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TAX1BP1,uniProtId:Q86VP1-1,ncbiNodeId:9606,antigenRange:406-540,antigenLength:789,antigenImageFileName:PA5-55076_TAX1BP1_Q86VP1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55076_TAX1BP1_Q86VP1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2648242

Product Specific Information

Immunogen sequence: ADAVAELKLN AMKKDQDKTD TLEHELRREV EDLKLRLQMA ADHYKEKFKE CQRLQKQINK LSDQSANNNN VFTKKTGNQQ KVNDASVNTD PATSASTVDV KPSPSAAEAD FDIVTKGQVC EMTKEIADKT EKYNK

Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.

Target Information

This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.