Thermo Fisher Scientific SPO11 Polyclonal Antibody, MaxPab
SPO11 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, Western blot에 적합합니다. 인간 시료에 반응하며, PBS(pH 7.4) 용액에 보존된 비결합형 항체입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | SPO11 (NP_937998, 1 a.a. ~ 358 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein Sequence:
MAFAPMGPEA SFFDVLDRHR ESLLAALRRG GREPPTGGSR LASRFEDSVG LQMVSHCTTR
KIKSDSPKSA QKFSLILKIL SMIYKLVQSN TYATKRDIYY TDSQLFGNQT VVDNIINDIS
CMLKVSRRSL HILSTSKGLI AGNLRYIEED GTKVNCTCGA TAVAVPSNIQ GIRNLVTDAK
FVLIVEKDAT FQRLLDDNFC NKLSPCIMIT GKGVPDLNTR LLVKKLWDTF HVPVFTLVDA
DPHGIEIMCI YKYGSMSMSF EAHHLTVPAI RWLGLLPSDL KRLNVPKDSL IPLTKRDQMK
LDSILRRPYV TCQPFWRKEM EIMADSKMKA EIQALTFLSS DYLSRVYLPN KLKFGGWITarget Information
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently linked to the 5′ end of DSBs and is essential for their formation. The human SPO11 protein shares sequence similarity and conserved features with the yeast meiotic recombination protein and belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been identified, though only two full-length forms are well characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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