Thermo Fisher Scientific ROBO1 Polyclonal Antibody

Applications and Tested Dilutions

Product Specifications

Product Specific Information

Positive test controls include: 293T, U-251MG, HeLa, Mouse brain, Rat brain.
The target is usually found in the following locations: Cell membrane, Cell projection, Single-pass type I membrane protein, axon.

Immunogen sequence:
AAVMQKTRPA KKLKHQPGHL RRETYTDDLP PPPVPPPAIK SPTAQSKTQL EVRPVVVPKL PSMDARTDRS SDRKGSSYKG REVLDGRQVV DMRTNPGDPR EAQEQQNDGK GRGNKAAKRD LPPAKTHLIQ EDILPYCRPT FPTSNNPRDP SSSSSMSSRG SGSRQREQAN VGRRNIAEMQ VLGGYERGED NNEELEETES

Target Information

Specialized cells at the midline, which separates the left and right halves of the CNS, have roles in directing growth cone behavior. In vertebrates, midline cells produce guidance cues such as nectins and slit, which act as attractants and repellents. Robo acts as a receptor for the repellent Slit and functions in a cell-autonomous fashion.
Robo1 and Robo2 are human homologs of the Drosophila protein Roundabout. Robo1 is homologous to the C. elegans gene sax3, and Robo2 to the zebrafish gene astray.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.