Thermo Fisher Scientific HSD17B4 Polyclonal Antibody
Rabbit polyclonal antibody targeting human HSD17B4 protein. Validated for WB, IHC(P), and ICC/IF applications. Purified via antigen affinity chromatography and supplied as liquid form in PBS with glycerol. For research use only.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HSD17B4. Recombinant protein control fragment (Product #RP-93146). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789912 |
Product Specific Information
Immunogen sequence:
LRFDGRVVLV TGAGAGLGRA YALAFAERGA LVVVNDLGGD FKGVGKGSLA ADKVVEEIRR RGGKAVANYD SVEEGEKVVK TALDAFG
Target Information
Peroxisomal multifunctional enzyme type 2 is a protein encoded by the HSD17B4 gene in humans.
This bifunctional enzyme participates in the peroxisomal β-oxidation pathway for fatty acids and catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.
Defects in this gene can cause D-bifunctional protein deficiency (DBPD). A pseudogene is located on chromosome 8, and multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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